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How to Access API endpoints from custom domain

Hi All,
We have cloned the open emr in a custom domain. Am new to this emr platform. while I was reading the API documentation I found that the end points for accessing the different type of information. But here in our scenario, we have mapped it to a custom domain. How can we access the APi endpoints using our custom domain. say as (http://www.mydomain.com/apis/api/patient). Could anyone please help me how to handle this. since I am new to this platform, could someone guide me how it needs to be approached.
Thanks,
Pradeep.S