Yes, it is possible. Thanks for bringing this thread to life again.
Are you using the MySQL database?
There is something called Master - Master Replication.
I am working through this in an attempt to get it working.
What I have done so far is to do a complete install of OpenEMR on a laptop. Setup the replication process to sync the laptop to the server. Copied the database from the server to the laptop over the weekend so that data would be identical. On Monday take the laptop out of the office and use it in the field. Monday afternoon, brought the laptop back to the office and what should happen is all the data that was changed out in the field should sync automatically to the office server.
This is the scenario that I am working towards. I will update once I take the laptop out in the field and come back.