Edit layout will save in some sections but not others

Trying to rename and add fields, specifically rename Misc tab and fields below. The changes appear to store and save but if I change the page or refresh then check them, they are all back to the default. Now I can edit the who tab without issue, but not Misc which was where we wanted to do the bulk of our customization. Anyone come across this. Clean install of latest version on Ubuntu 18.04

@MKunkle,
Could you please ensure that max_input_vars is set to 3000 in /etc/php/5.6/php.ini file.
Note: Based on your php version, change the folder path.

Thanks,
ViSolve