I used this command once without openemr loaded and once with openemr loaded. The output was the exactly the same:
robert@robert-ideacentre-AIO-520-22IKU:~$ sudo ss -ltpn
[sudo] password for robert:
State Recv-Q Send-Q Local Address:Port Peer Address:Port
LISTEN 0 128 127.0.0.1:33383 0.0.0.0:* users:(("containerd",pid=1010,fd=12))
LISTEN 0 50 0.0.0.0:139 0.0.0.0:* users:(("smbd",pid=1897,fd=35))
LISTEN 0 128 0.0.0.0:80 0.0.0.0:* users:(("docker-proxy",pid=2712,fd=4))
LISTEN 0 10 192.168.1.48:53 0.0.0.0:* users:(("named",pid=1001,fd=28))
LISTEN 0 10 172.17.0.1:53 0.0.0.0:* users:(("named",pid=1001,fd=27))
LISTEN 0 10 172.18.0.1:53 0.0.0.0:* users:(("named",pid=1001,fd=26))
LISTEN 0 10 192.168.1.49:53 0.0.0.0:* users:(("named",pid=1001,fd=25))
LISTEN 0 10 127.0.0.1:53 0.0.0.0:* users:(("named",pid=1001,fd=22))
LISTEN 0 128 127.0.0.53%lo:53 0.0.0.0:* users:(("systemd-resolve",pid=673,fd=13))
LISTEN 0 5 127.0.0.1:631 0.0.0.0:* users:(("cupsd",pid=747,fd=8))
LISTEN 0 128 127.0.0.1:953 0.0.0.0:* users:(("named",pid=1001,fd=23))
LISTEN 0 128 0.0.0.0:443 0.0.0.0:* users:(("docker-proxy",pid=2691,fd=4))
LISTEN 0 50 0.0.0.0:445 0.0.0.0:* users:(("smbd",pid=1897,fd=34))
LISTEN 0 50 [::]:139 [::]:* users:(("smbd",pid=1897,fd=33))
LISTEN 0 128 [::]:80 [::]:* users:(("docker-proxy",pid=2718,fd=4))
LISTEN 0 32 *:21 *:* users:(("proftpd",pid=1944,fd=0))
LISTEN 0 10 [::]:53 [::]:* users:(("named",pid=1001,fd=21))
LISTEN 0 5 [::1]:631 [::]:* users:(("cupsd",pid=747,fd=7))
LISTEN 0 128 [::1]:953 [::]:* users:(("named",pid=1001,fd=24))
LISTEN 0 128 [::]:443 [::]:* users:(("docker-proxy",pid=2698,fd=4))
LISTEN 0 50 [::]:445 [::]:* users:(("smbd",pid=1897,fd=32))
robert@robert-ideacentre-AIO-520-22IKU:~$